Cymbalta is a pregnancy category C drug. When studied in animals, it showed numerous different effects. Some of the adverse effects of taking this drug include behavioral changes such as getting startled when hearing a noise. SNRIs also are considered an option during pregnancy, including duloxetine (Cymbalta) and venlafaxine (Effexor XR). However, research suggests that taking SNRIs at the end of pregnancy is associated with postpartum hemorrhage. Just curious if anyone has taken or has heard of anyone taking cymbalta during their pregnancy. It's a class C drug and I'm very nervous. I've searched the internet high and low and didn't get much answers. First Cymbalta Class Action Lawsuit In 2012, Eli Lilly and Company, the manufacturer and marketer of Cymbalta was facing its first case filed in Federal District Court over withdrawal reactions when patients stopped taking the antidepressant medication. Duloxetine, or Cymbalta, use during pregnancy and the safety for the baby is a common question. Duloxetine and PregnancY Since depression is diagnosed more commonly in women and pregnancy triggers or worsens depression, it is no wonder that concern for the health and wellness of the baby comes to mind. However, Cymbalta may cause problems in a newborn if you take the medicine during the third trimester of pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine. There are some situations where it may not be safe to take Cymbalta, and pregnancy is one of them. The FDA has classified Cymbalta as a pregnancy Category C medication, meaning that it does appear to cause side effects to the fetus in animal studies. Animal studies have revealed evidence of teratogenicity. There are no controlled data in human pregnancy. If treating pregnant women with duloxetine during the third trimester, the physician may wish to consider tapering this drug. Although duloxetine (cymbalta) is used fairly commonly in women of child-bearing age, information regarding its reproductive safety is limited. Cymbalta (duloxetine), a drug prescribed for neuropathic pain associated with diabetic peripheral neuropathy, depression, and anxiety. Side effect, dosage, and drug interaction information included.